The last mile of disease elimination is often the most anticipated as countries approach their elimination targets. However, this phase is also the most challenging, requiring significant financial investment and carefully tailored strategies to ensure the most effective technologies and tools reach the communities that need them most. At the 2023 Reaching the Last Mile Forum, global donors announced a milestone expansion of the Reaching the Last Mile Fund (RLM Fund) from $100 million to $500 million. This landmark investment aims to bolster global efforts to eliminate onchocerciasis and lymphatic filariasis (LF) in Africa and Yemen1. Despite this progress, critical questions persist: how, where, and to whom should these resources be allocated to achieve maximum impact?

Recognizing the urgency of these challenges, GLIDE hosted a stakeholder engagement roundtable on November 14, 2024, on the sidelines of the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meeting in New Orleans, Louisiana, USA. The focus was on moxidectin, a promising tool for accelerating the elimination of onchocerciasis.